Advancing Thyroid Molecular Science
Afirma® 2024
Research Collection:
Thyroid Insights & Data
A comprehensive compilation of novel research demonstrating Afirma’s whole-transcriptome capabilities in advancing thyroid cancer diagnostics.
A Comprehensive Review of Afirma’s Novel Research Presented in 2024
Through whole-transcriptome analysis of every thyroid nodule we receive, Afirma has built one of the most comprehensive genomic databases in thyroid cancer diagnostics.
This powerful approach not only serves as the foundation for Afirma GSC, but also creates the potential for novel research that advances our understanding of thyroid cancer like the molecular diagnostic studies featured in this collection.
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Featured Studies
This document is a collection of all 8 Afirma GSC posters presented in collaboration with Veracyte in 2024, with succinct summaries and explanations of each. Additional information on 2 manuscripts and 3 publications on Afirma GSC with external authors is also included.
Retrospective Analysis of mRNA Expression Based Signatures of Thyroid Tumor Invasion and Metastases
The validation of 2 new molecular signatures created to rule out the risk of clinically significant thyroid tumor invasion and metastasis.
First Report of Pre-operative Detection of Two TERT Promoter Mutations Within a Papillary Thyroid Carcinoma
A unique case study of two distinct TERT promoter mutations present in the same cancer, the first of its kind to our knowledge.
Polyamine and Methionine Metabolism Gene Expression Analysis in Thyroid Tumors
An extensive interrogation of the genes found in the polyamine methionine cycle for correlation with thyroid tumor cytologic, molecular, and clinical risk.
2024 has proven to be a fantastic demonstration of the novel research that’s possible with Afirma GSC. This document is a collection of this research: presentations that have included compelling case studies, demonstrated new signatures, and furthered our understanding of thyroid nodular disease.”
Medical Director,
Endocrinology
Explore Research Opportunities with Afirma
If you have any questions about the studies presented in this document or would like to discuss ideas for your own research, request a meeting with our friendly Afirma Medical Science Liaison (MSL) team.